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Effect of varying VIP concentration on SCN population behavior. For each VIP concentration, the mean (circle) and SD (error bars) were computed from 10 independent runs. (A) Mean Per mRNA (solid line) and firing-frequency (dashed line) amplitudes as a function of VIP application. (B) The SI at the 10th cycle of our simulations versus % increases in VIP concentration. (C) Average period of the model network versus % increases in VIP.
