Table 1.

Microarray Analysis of Luteolin Effects on Gene Expression in MCF-7 Cells

Down	%	Up	%	Total	%
840	1.54	772	1.41	1612	2.95

MCF-7 cells were treated for 5 hours with estradiol (5 nM) or estradiol (5 nM) plus luteolin (17.5 μM). Cells were harvested for RNA preparation and microarray analyses. Luteolin regulated genes were determinate by dChip comparison of the expression patterns between the cells treated with estradiol alone or estradiol plus luteolin.