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Foxa2 is required in β cells for KATP-channel steady-state mRNA expression. Reverse-transcription PCR analysis of Kir6.2 (a) and SUR1 (b) mRNA levels in islet RNA from control (unfilled bars) and Foxa2loxP/loxP; Ins.Cre (cross-hatched bars) mice, which were normalized to those of HPRT. Radioactive bands were quantified by phosphorimager analysis. Bars represent values ± SEM, with number indicated in parenthesis. *, P < 0.05; Foxa2loxP/loxP; Ins.Cre vs. control mice.
