TABLE 3.

Parameters obtained from the operational model of allosteric modulation, where A is propionate (fixed concentrations) and B is 4-CMTB (variable concentrations)

	FFA2 WT		FFA2 L173A		FFA2 (ECL2 FFA3)
	Mean	S.E.M.	Mean	S.E.M.	Mean	S.E.M.
logKA	−3.20	0.29	−3.13	0.30	−3.82	0.27
logKB	−5.26	0.43	−5.27	0.37	−6.43	0.26
logα	1.88	0.59	0.82	0.56	0.13	0.42
logβ	0.31	0.11	0.66	0.21	0.23	0.11
logαβ	2.19	0.71	1.48	0.78	0.36	0.53
αβ	155		30*		2.3**

^* P < 0.05 according to one-way ANOVA with Newman-Keuls multiple comparisons post hoc analysis.

^** P < 0.01 according to one-way ANOVA with Newman-Keuls multiple comparisons post hoc analysis.