Table 1.

Histologic features assessed semiquantitatively in liver biopsy specimens

Feature	Assessment
Florid duct lesion	Absent	Present
Granuloma	Absent	Present
Bile duct loss	Absent	Present in < 50% of p.t.	Present in > 50% of p.t.
Bile duct damage	Absent	Present in < 1/3 of p.t.	Present in 1/3–2/3 of p.t.	Present in almost all p.t.
Ductular reaction	Absent	Mild	Moderate	Severe
Chronic portal inflammation	Absent	Mild	Moderate	Severe
Piecemeal necrosis	Absent	Mild	Moderate	Severe
Lobular necro-inflammatory activity	Absent	Mild	Moderate	Severe
Steatosis	Absent	Mild	Moderate	Severe
Fibrosis	Absent (0)	Portal (I)	Septal (II)	Bridging (III)
Cirrhosis	Absent	Present (IV)
Cholestasis	Absent	Present

p.t., portal tracts. Roman numerals equate descriptive designations to numerical fibrosis scores.