Table 2.
Statistically significant differences in histologic features between the biopsy specimens of the primary biliary cirrhosis (PBC) group and those of the chronic hepatitis C virus (CHCV) group (corresponding numbers of patients in parentheses)
| PBC | CHCV | P-value | |
|---|---|---|---|
| Total number of biopsies | 83 | 152 | |
| Florid duct lesion | 5 (4) | 0 | 0.0048† |
| Piecemeal necrosis | 0.0002† | ||
| Absent | 50 (32) | 52 (33) | 0.0014* |
| Mild | 23 (16) | 69 (40) | |
| Moderate | 6 (4) | 23 (16) | |
| Severe | 4 (2) | 8 (7) | |
| Lobular necroinflammatory activity | < 0.0001† | ||
| Absent | 23 (17) | 10 (7) | < 0.0001* |
| Mild | 46 (33) | 95 (49) | |
| Moderate | 9 (8) | 35 (26) | |
| Severe | 5 (3) | 12 (10) | |
| Stage of fibrosis/cirrhosis | < 0.0001† | ||
| Absent | 38 (26) | 23 (18) | < 0.0001* |
| Portal (I) | 14 (11) | 55 (31) | |
| Septal (II) | 17 (13) | 33 (22) | |
| Bridging (III) | 7 (6) | 24 (17) | |
| Cirrhosis (IV) | 7 (2) | 17 (11) | |
| Steatosis | < 0.0001† | ||
| Absent | 62 (38) | 68 (33) | < 0.0001* |
| Mild | 19 (15) | 73 (41) | |
| Moderate | 1 (1) | 10 (9) | |
| Severe | 1 (1) | 1 (1) |
†
Comparison of how commonly a feature was found (presence vs. absence);
*
the scoring distribution (absent, mild, moderate, severe).