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. 2011 Jun;77(11):3669–3675. doi: 10.1128/AEM.02000-10

Table 4.

A. nidulans wild-type, cclAΔ, cclAΔ mdpGΔ, and alcA(p)::mdpE strains exhibit similar patterns of susceptibility to 2-OHa

2-OH treatment (μM) Growth of strain in RPMI with indicated 2-OH concn
Growth of alcA::mdpE in RPMI + 30 mM cyclopentanone
WT cclAΔ cclAΔ mdpGΔ alcA::mdpE
567
284
142 + +
71 + + + + +
35 + + + + +
18 + + + + +
9 + + + + +
Untreated control + + + + +
a

The patterns of susceptibility suggest that the monodictyophenone gene cluster does not include a resistance-encoding gene to protect the fungus from the metabolites produced by this pathway. The symbols + and − denote growth and no growth, respectively. Growth was assessed by microscopic visualization of wells 48 h post treatment.