Fig. 1.

Domain organization of the Skn7p and Yap1p transcription factors. (A) Schematic diagram of major domains of the Yap1 protein, including the positions of the two cysteine-rich domains (n-CRD and c-CRD) and the nuclear export sequence (NES). Disulfide bonds formed in response to hydrogen peroxide stress are also shown. (B) Domain organization of the Skn7 transcription factor, showing the heat shock factor like DNA-binding domain (HSF), the coiled-coil domain (CC), the receiver domain (Receiver), and the glutamine-rich (Q) domains. Amino acid positions of domains and of critical residues mentioned in the text are indicated above both drawings.