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. 2001 Sep 1;15(17):2307–2319. doi: 10.1101/gad.200101

Figure 2.

Figure 2

Growth retardation and expression analysis of Cutl1 mutant mice. (A,B) View of a wild-type mouse (A) and its surviving Cutl1Z/Z littermate (B) (on the C57BL/6 × 129/Sv background) at postnatal day 37. (C) Delayed growth of Cutl1Z/Z mice maintained on the OF1 background. The weight of wild-type (n = 3) and Cutl1Z/Z (n = 6) mice was measured at regular intervals after birth. (D–J) Cutl1 expression in the developing incisor tooth (D), pituitary (E), thyroid (F), salivary gland (G), kidney (H), tongue muscle (I), and testis (J). X-Gal staining was performed on cryosections of Cutl1Z/Z fetuses at day 14.5 (D,E, I) or day 16.5 (F–H) and of the testis of a 3-month-old Cutl1+/Z mouse (J). (AP) Anterior pituitary; (D) collecting duct; (DP) dental papilla; (ELS) elongating spermatid; (ES) elongated spermatid; (G) glomerulus; (IE) inner enamel epithelium; (M) muscle; (MF) muscle fiber; (OE) outer enamel epithelium; (PS) pachytene spermatocyte; (RP) Rathke's pouch; (RS) round spermatid; (S) S-shaped body; (T) tubule; (U) ureteric tip.