Table 3.

Summary estimates of sensitivity, specificity, positive likelihood ratio (LR) and negative LR for the Centor score, calculated using a bivariate random effects model

Centor score	No. of studies	Sensitivity (95% CI)	Specificity (95% CI)	+ LR (95% CI)	- LR (95% CI)
≥ 1	11	0.95 (0.91 to 0.97)	0.18 (0.12 to 0.26)	1.16 (1.08 to 1.25)	0.27 (0.16 to 0.46)
≥ 2	12	0.79 (0.71 to 0.86)	0.55 (0.45 to 0.65)	1.76 (1.51 to 2.07)	0.37 (0.29 to 0.48)
≥ 3	11	0.49 (0.38 to 0.60)	0.82 (0.72 to 0.88)	2.68 (1.92 to 3.75)	0.62 (0.52 to 0.74)
4	11	0.18 (0.12 to 0.27)	0.95 (0.92 to 0.97)	3.85 (2.05 to 7.24)	0.86 (0.78 to 0.93)