Table 1.

Clinical studies evaluating outcome of lifestyle interventions for obese adults and children with NAFLD

Author	Patients (n)	Study type	Therapy	Duration	Outcome
Franzese et al. [38]	58	Case series	Diet and exercise	Six months	85% of patients with NAFLD (19/33) with normalization or improvement in US findings of NAFLD
Huang et al. [11]	23	Pilot study	Diet	one year	NASH improved In 60% of patients
Johnson, NA [10]	19	Randomized, controlled trial	Exercise	four weeks	Reduction of hepatic triglyceride concentration, visceral adipose tissue volume and hepatic free fatty acids
Nobili V et al. [16]	53	Randomized, controlled trial	Diet and exercise	24 months	Children experienced weight loss and improved liver histology after lifestyle intervention
Oza et al. [39]	22	Pilot study	Diet	six months	BMI and steatosis reduced in 86% of patients who completed the study (only 32% of patients completed the study)
Palmer et al. [40]	39	Case series	Diet and exercise	2 to 111 months	Liver enzymes improved in patients with weight loss
Promrat et al. [37]	31	Randomized, controlled trial	Diet and exercise	48 weeks	More patients with lifestyle intervention had reduction in NAS score in comparison with control group
St. George et al. [9]	152	Randomized trial	Diet and exercise	three months	Reduction of liver enzymes in both the low-intensity and moderate-intensity groups
Ueno et al. [8]	25	Non-randomized, controlled trial	Diet and exercise	three months	Steatosis improved in the intervention group
Viljanen et al. [12]	34	Case Series	Diet	six weeks	Decreased liver volume and liver fat content, improved hepatic insulin resistance