Table 2.
Baseline parameters of treatment naive patients subgrouped by different manifestation revealed a significant decrease in cholesterol in hepatic patients.
| n | Limits of normal | Hepatic | Neurological | Mixed | Asymptomatic | p-value | |
| ALT | 139 | f: -35 U/l m: -50 U/l |
101.9 (7-3743) |
22 (10-140) |
28.2 (17-272) |
20 (7-168) |
>0.001 |
| AST | 135 | f: -35 U/l m: -50 U/l |
76.9 (13-2106) |
21.2 (6-58) |
32 (19-108) |
26.4 (11-102) |
>0.001 |
| Bilirubin | 122 | < 1.0 mg/dl |
1.1 (0.2-39) |
0.9 (0.1-3.8) |
0.6 (0.2-1.4) |
0.5 (0.2-0.9) |
0.009 |
| Albumin | 103 | 30-50 g/l |
41 (23-55) |
45.2 (38-52) |
43 (35-57) |
46.3 (35-52) |
0.001 |
| TG | 64 | < 150 mg/dl | 110 (33-888) |
120 (63-200) |
124 (40-249) |
60 (59-100) |
0.300 |
| Cholesterol | 70 | < 200 mg/dl |
158 (66-319) |
194 (123-243) |
186 (145-244) |
195 (173-294) |
0.004 |
| HDL | 14 | >50 mg/dl | 57 (42-76) |
53 (48-77) |
60 (56-64) |
- | 0.923 |
| LDL | 12 | < 160 mg/dl | 96 (63-218) |
161 (156-166) |
88 (81-95) |
- | 0.207 |
| BMI | 26 | 18.5-25 kg/m² | 20.6 (14.9-24.5) |
26.2 (20.3-30.8) |
23.1 (14.8-28.6) |
19.7 (19.7-19.7) |
0.126 |
Median serum cholesterol and triglycerides presented within normal range.