Table 5.

Poisson multivariate regression model for number of flares during follow-up of 12 months by sex

		Females (N = 43,304)			Males (N = 134,333)
		IRR	95% CI	p-value	IRR	95% CI	p-value
Age	< 50	1.00	(ref.)		1.00	(ref.)
	50 - 59	1.66	(1.49, 1.85)	< .0001	0.83	(0.80, 0.85)	< .0001
	60 - 69	1.93	(1.73, 2.16)	< .0001	0.76	(0.73, 0.79)	< .0001
	70 - 79	1.69	(1.51, 1.90)	< .0001	0.56	(0.53, 0.60)	< .0001
	80 - 89	1.31	(1.12, 1.52)	0.001	0.53	(0.48, 0.59)	< .0001
Comorbidities:
Cardiometabolic*		1.60	(1.48, 1.74)	< .0001	1.10	(1.06, 1.13)	< .0001
Diabetes		1.48	(1.35, 1.63)	< .0001	0.97	(0.93, 1.02)	0.262
Gastrointestinal		0.86	(0.78, 0.96)	0.005	1.07	(1.02, 1.13)	0.011
Hematological		1.03	(0.88, 1.20)	0.720	0.94	(0.84, 1.06)	0.340
Myopathy		1.21	(0.50, 2.91)	0.670	0.84	(0.50, 1.42)	0.509
Osteoporosis		0.88	(0.78, 1.00)	0.044	1.11	(0.99, 1.25)	0.076

IRR = Incidence rate ratio.

* Cardiometabolic disease include congestive heart failure, ischaemic heart disease, hypertension, cerebrovascular disease, peripheral arterial disease, dyslipidemia.