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. 2001 Sep 15;15(18):2396–2407. doi: 10.1101/gad.918201

Figure 5.

Figure 5

Cdc20 and Cdh1 N-terminal inhibitors do not bind APC. (A) Full-length hCdc20 and hCdh1 bind to iAPC immuno-purified from Xenopus extracts on αCdc27-coated beads, as do the first 170 amino acids of hCdc20 and 173 amino acids of hCdh1, however APC bound to αCdc27-coated beads fails to bind the N-terminal 120 amino acids of hCdc20 or 125 amino acids of hCdh1 above control beads. (B) Binding of full-length hCdc20 and hCdh1 to iAPC on beads in the presence of 5 or 10 μM N-terminal peptides of hCdc20 and hCdh1.