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. 2011 May 25;6:26. doi: 10.1186/1749-8104-6-26

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Copyright ©2011 Ori-McKenney and Vallee; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Loa/Loa neurons display a defect in axon extension in vivo. (A,B) Individual neurons from Oregon Green stained wild-type (A) or Loa/Loa (B) brain sections with a visible axon (thin arrowhead), or no visible axon (wide arrowhead). Neurons from both the cortical plate (CP) and intermediate zone (IZ) were analyzed. Scale bars = 20 μm. (C) Quantification of the percentage of wild-type or Loa/Loa neurons with a visible axon. Only neurons with visible leading processes were scored for an axon, or lack thereof. Error bars represent the standard deviation. (D) Quantification of the percentage of wild-type and Loa/Loa axons that were shorter or longer than 40 μm.