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. 2001 Apr 1;29(7):1514–1523. doi: 10.1093/nar/29.7.1514

Figure 4.

Figure 4

GSH levels in embryonic livers at late E12.5 stage. GSH levels were determined in MTF-1 wild-type (n = 3), heterozygous (n = 9) and knockout (n = 3) liver samples via a HPLC-based method (29). No significant reduction in GSH in MTF-1 knockout livers was observed. Note that the GSH level in knockout embryos at E12.5 is at least as high, if not higher, than in wild-type and heterozygous embryos (even though mRNA levels for γ-GCShc are reduced in MTF-1 knockout embryos at later stages; 16).