Table 3. MTF-1 target genes described in the literature.

Gene	Source of evidence	MRE in regulatory regiona	Binding of MTF-1 to oligob
Stress-responsive genes
MT-I	Detailed in vivo and in vitro evidence (4,16)	6 MREs in promoter (M)	++++
ZnT-1	Detailed in vivo and in vitro evidence (59)	3 MREs in promoter (M)
γ-GCS	Conflicting in vivo data, but promoter responsive to MTF-1 in transient transfections (16)	1 MRE in promoter, 1 in leader (H)	+/+++
γ-Glutamyltranspeptidase	Database search (16)	3 MREs in promoter (M)
PlGF	In vivo and in vitro evidence (60)	2 MREs in promoter (M)

^a(M), mouse; (H), human. Human was considered when mouse sequence was unavailable.

^bMREs were tested only from the indicated subset of genes.