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. 2011 Jun 30;6(6):e20252. doi: 10.1371/journal.pone.0020252

Figure 5. Inhibitory effect of MG132 on RSV replication.

Figure 5

(A) Interaction map of the MG132 induced immune signaling molecules. MG132 induced immune signaling related genes were analyzed using protein interaction data retrieved from STRING. Green and yellowish green colored genes were up-regulated by MG132 more than 2 fold and 1.5 fold, respectively. Grey colored genes were up-regulated by MG132 less than 1.5 fold. Black lines indicate protein-protein interactions with confidence coefficient higher than 0.7. (B) The effect of MG132 on RSV replication was measured in plaque formation. Ribavirin was used as a positive control. The replication of RSV was presented as % of DMSO control.