Table 5.

Genes that have a general association (P-value < 0.05) with the overall glioblastoma survival

Gene Symbol	Probe Identifier	P-value	Hazard Ratio1	Relevant literature references
Tgfa	205015_s_at	0.0002	0.12 (0.04-0.37)	[28]G
Sirpa	202895_s_at	<.0001	0.24 (0.14-0.41)	[26]G
Ctbp2	210835_s_at	<.0001	0.28 (0.16-0.48)	[101]O
Eef1e1	213907_at	<.0001	0.37 (0.23-0.61)	[102]O
Mapk3	212046_x_at	0.0041	0.43 (0.24-0.76)	[103]O
Actr2	200727_s_at	<.0001	0.43 (0.29-0.63)	[24]G
Igh@	211637_x_at	0.0167	0.44 (0.23-0.86)	n/a
Plcg1	216551_x_at	<.0001	0.46 (0.31-0.68)	[26]G
Mgat3	209764_at	<.0001	0.51 (0.37-0.71)	[26]G
Lrp10	201412_at	0.0041	0.60 (0.42-0.85)	[24]G
Idh1	201193_at	0.0051	0.60 (0.42-0.86)	[24]G
Tmem8b	207839_s_at	<.0001	0.60 (0.46-0.77)	n/a
Ccna2	203418_at	<.0001	0.60 (0.49-0.75)	[104]O
Topors	204071_s_at	0.0007	0.61 (0.46-0.81)	[26]G
Rpl37a	213459_at	0.0164	0.66 (0.47-0.93)	[90]G
Mdm2	217373_x_at	<.0001	0.69 (0.61-0.78)	[26]G
E2f3	203693_s_at	0.06722	0.75 (0.55-1.02)	[28]G
Mdfic	211675_s_at	0.0006	0.78 (0.68-0.90)	[105]O
Sod2	215078_at	<.0001	0.80 (0.73-0.88)	[25]G
Akr1c3	209160_at	0.0014	0.83 (0.73-0.93)	[26]G
Thbs4	204776_at	0.0007	1.18 (1.07-1.30)	[106]O
Shc3	206330_s_at	0.0031	1.32 (1.10-1.59)	[28]G
Pik3r1	212249_at	0.0145	1.34 (1.06-1.69)	[20]G
Nkx2-5	206578_at	0.0027	1.38 (1.12-1.70)	[107]O
Hras	212983_at	0.0187	1.42 (1.06-1.90)	[85]G
Bhlhb9	213709_at	0.0192	1.42 (1.06-1.92)	[108]O
C9orf95	219147_s_at	0.0004	1.43 (1.17-1.73)	[109]O
C17orf101	219254_at	0.0085	1.46 (1.10-1.94)	[110]O
Nol3	59625_at	<.0001	1.46 (1.21-1.76)	[111]O
Rangap1	212125_at	0.0225	1.47 (1.06-2.05)	[26]G
Ftsj2	222130_s_at	0.017	1.48 (1.07-2.05)	[112]O
Rrm1	201476_s_at	0.0006	1.49 (1.19-1.87)	[27]G
Jag2	209784_s_at	0.0351	1.63 (1.03-2.57)	[24]G
Tnpo1	212635_at	0.0054	1.89 (1.20-2.96)	n/a
Myo7a	211103_at	0.0033	1.97 (1.25-3.10)	[113]O
Actr2	200729_s_at	0.0001	2.18 (1.47-3.23)	[24]G
Csf1	209716_at	<.0001	2.33 (1.65-3.27)	[26]G
Ank1	208352_x_at	0.0003	2.38 (1.49-3.82)	[24]G
B3galnt1	211379_x_at	<.0001	2.40 (1.76-3.28)	[114]O
Kras	214352_s_at	0.002	2.44 (1.38-4.31)	[85]G
Ewsr1	210012_s_at	0.0005	2.49 (1.49-4.15)	[26]G
Sec24c	202361_at	<.0001	2.84 (1.76-4.60)	n/a
Rpl10l	217559_at	<.0001	2.95 (1.83-4.74)	[115]O
Ighg1	211908_x_at	0.0007	3.41 (1.68-6.93)	[116]O
Ighg1	211693_at	0.0007	4.33 (1.86-10.04)	[116]O

n/a, No association with any type of cancer found in literature;

¹ Hazard ratio estimate (95% confidence interval);

² Borderline significant (P-value < 0.1) included for completeness;

^G Gene confirmed in an independent glioblastoma multiforme study; the number between square brackets denotes the corresponding literature reference;

^O Gene confirmed in an independent study on any other type of cancer; the number between square brackets denotes the corresponding literature reference.