Table 3.
Amplitude and latency of ERP components for target and standard stimuli and for the CNV periods
| Amplitude | Latency | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Controls | RRMS | BMS | p | Controls | RRMS | BMS | p | |||
| ERPs | Mean ± SD | ERPs | Mean ± SD | |||||||
| (○) eN1 | 0.001 a | |||||||||
| Valid | -0.85 ± 2.4 | 0.47 ± 1.2 | 0.97 ± 1.2 | |||||||
| Invalid | -0.63 ± 0.9 | 0.33 ± 1.5 | 0.96 ± 2.1 | |||||||
| (○) P1 | 0.020 a,b,c | (○) P1 | 0.558 | |||||||
| Valid | 1.59 ± 1.8 | 1.86 ± 1.3 | 1.59 ± 1.0 | 132 ± 6 | 135 ± 6 | 136 ± 7 | ||||
| Invalid | 1.17 ± 1.5 | 1.19 ± 1.2 | 2.09 ± 2.1 | 133 ± 7 | 133 ± 5 | 133 ± 6 | ||||
| (○) N1 | 0.419 | (○) N1 | < 0.001 a,c | |||||||
| Valid | - 0.95 ± 1.2 | - 1.41 ± 1.1 | - 1.01 ± 1.7 | 174 ± 11 | 179 ± 10 | 188 ± 8 | ||||
| Invalid | -0.98 ± 1.5 | -1.46 ± 1.1 | -0.81 ± 1.5 | 173 ± 11 | 181 ± 10 | 188 ± 9 | ||||
| (○) P3 | 0.294 | (○) P3 | 0.003 a,b,c,d | |||||||
| Valid | 4.99 ± 2.4 | 4.38 ± 4.8 | 4.56 ± 2.7 | 352 ± 1 | 371 ± 10 | 381 ± 18 | ||||
| Invalid | 5.67 ± 1.4 | 5.18 ± 1.5 | 4.61 ± 2.5 | 353 ± 13 | 375 ± 17 | 390 ± 12 | ||||
| (⊙) P2 | 0.232 | (⊙) P2 | < 0.001 a | |||||||
| Valid | 5.40 ± 2.8 | 5.37 ± 3.3 | 5.26 ± 3.7 | 219 ± 12 | 240 ± 13 | 241 ± 17 | ||||
| Invalid | 5.99 ± 3.7 | 6.25 ± 2.7 | 7.25 ± 1.5 | 226 ± 11 | 242 ± 12 | 249 ± 13 | ||||
| (⊙) N2 | 0.169 | (⊙) N2 | 0.002 a | |||||||
| Valid | -0.30 ± 1.7 | -0.16 ± 1.8 | -0.52 ± 3.8 | 252 ± 13 | 268 ± 10 | 271 ± 17 | ||||
| Invalid | -0.10 ± 2.6 | -0.81 ± 2.4 | -0.40 ± 3.1 | 262 ± 11 | 270 ± 12 | 269 ± 12 | ||||
| (⊙) P3 | 0.239 | (⊙) P3 | < 0.001 a | |||||||
| Valid | 8.95 ± 3.7 | 7.63 ± 4.3 | 7.13 ± 4.4 | 372 ± 19 | 397 ± 15 | 399 ± 20 | ||||
| Invalid | 9.81 ± 3.9 | 8.36 ± 4.1 | 9.22 ± 4.2 | 363 ± 20 | 381 ± 20 | 390 ± 17 | ||||
| (○) LN | -1.72 ± 1.1 | -1.80 ± 1.5 | -1.68 ± 1.5 | 0.718 | ||||||
| (⊙) LN | -2.23 ± 2.1 | -3.24 ± 2.0 | -1.13 ± 1.5 | 0.031 b | ||||||
| eCNV | -1.82 ± 1.7 | -0.87 ± 1.1 | -0.18 ± 2.2 | 0.035 a, c | ||||||
| cCNV | 1.13 ± 0.8 | -0.57 ± 0.8 | 0.89 ± 1.0 | 0.043 a, d | ||||||
| tCNV | 0.57 ± 0.6 | 0.96 ± 0.7 | 0.74 ± 0.9 | 0.632 | ||||||
Means and standard deviations (SD) of electrodes and regions of interest used for each ERP-component ANOVA analysis are shown. P values show main statistical effects involving the group factor.
[⊙ = target stimuli; ○ = standard stimuli].
a = p < 0.05 between control and both MS groups;
b = p < 0.05 between RRMS and BMS groups;
c = p = < 0.05 between control and BMS groups;
d = p < 0.05 between control and RRMS groups.