Table 2.
Association of E-cadherin with tumour stage, differentiation grade and lymph node status
| Cadherin low (IRS ≤ 9) n = 79 (65.8%) |
Cadherin high (IRS > 9) n = 41 (34.2%) |
P-value | |
|---|---|---|---|
| Tumor stage | 0.4451) | ||
| pT1 | 40 (50.6%) | 24 (58.5%) | |
| pT2 | 39 (49.4%) | 17 (41.5%) | |
| Differentiation grade* | 0.0182) | ||
| Grade I (well) | 7 (9.5%) | 7 (18.4%) | |
| Grade II (moderate) | 51 (68.9%) | 29 (76.3%) | |
| Grade III (poor) | 16 (21.6%) | 2 (5.3%) | |
| Sentinel node | 0.0051) | ||
| negative | 42 (53.2%) | 33 (80.5%) | |
| positive | 37 (46.8%) | 8 (19.5%) |
*Eight patients with differentiation grade not otherwise specified have been excluded
1) Fisher's exact test, 2) exact Mann-Whithey U test