Table 2.
14 selected differential expression genes.
| Gene Symbol | The 25 breast cancers | NKI-295 dataset | GIS-251 dataset | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| FNAB array | FFPE array | FFPE qPCR | FFPE vs. FNAB | FFPE vs. qPCR | Array | OS | DMFS | Array | OS | RFS | |
| P1 | P1 | P1 | r2 | r3 | P1 | P4 | P4 | P1 | P4 | P4 | |
| AKR7A3 | 0.001 | 0.000 | 0.000 | 0.701 | 0.653 | 0.000 | 0.000 | 0.248 | 0.000 | 0.284 | 0.787 |
| ANKRA2 | 0.001 | 0.009 | 0.021 | 0.522 | 0.390 | 0.000 | 0.021 | 0.071 | 0.000 | 0.064 | 0.139 |
| ANLN | 0.000 | 0.002 | 0.007 | 0.731 | 0.543 | 0.000 | 0.002 | 0.010 | 0.000 | 0.009 | 0.004 |
| CA12 | 0.000 | 0.000 | 0.000 | 0.607 | 0.710 | 0.000 | 0.010 | 0.299 | 0.000 | 0.358 | 0.468 |
| DNALI1 | 0.000 | 0.000 | 0.000 | 0.681 | 0.646 | 0.000 | 0.009 | 0.097 | 0.000 | 0.565 | 0.582 |
| ERBB2 | 0.000 | 0.008 | 0.000 | 0.370 | 0.815 | 0.000 | 0.005 | 0.024 | 0.000 | 0.006 | 0.001 |
| ESR1 | 0.000 | 0.000 | 0.000 | 0.787 | 0.862 | 0.000 | 0.004 | 0.030 | 0.000 | 0.698 | 0.742 |
| FUT3 | 0.001 | 0.001 | 0.003 | 0.542 | 0.444 | 0.000 | 0.061 | 0.009 | 0.000 | 0.023 | 0.287 |
| GREB1 | 0.001 | 0.001 | 0.000 | 0.732 | 0.711 | 0.000 | 0.054 | 0.667 | 0.000 | 0.023 | 0.487 |
| KIAA1407 | 0.000 | 0.000 | 0.010 | 0.460 | 0.337 | 0.000 | < 0.001 | 0.000 | 0.000 | 0.006 | 0.197 |
| KIF2C | 0.000 | 0.001 | 0.020 | 0.710 | 0.647 | 0.000 | < 0.001 | 0.000 | 0.000 | 0.022 | 0.004 |
| LONRF2 | 0.001 | 0.007 | 0.004 | 0.398 | 0.588 | 0.000 | 0.001 | 0.168 | 0.000 | 0.294 | 0.393 |
| MAPT | 0.000 | 0.000 | 0.000 | 0.740 | 0.677 | 0.000 | 0.007 | 0.023 | 0.000 | 0.001 | 0.014 |
| PGR | 0.000 | 0.000 | 0.000 | 0.870 | 0.674 | 0.000 | < 0.001 | < 0.001 | 0.000 | 0.022 | 0.206 |
FNAB, fine needle aspiration biopsy; FFPE, formalin-fixed, paraffin-embedded tissue; qPCR, Quantitative RT-PCR; OS, Overall survival; DMFS, Distant metastasis free survival; RFS, Relapse free survival; 1P-value of ANOVA test among the 4 ER/Her2 groups; 2Correlation coefficient, Pearson correlation test between FFPE array and FNA array (value in boldface type is statistically significant, P < 0.05); 3Correlation coefficient, Pearson correlation test between FFPE array and FFPE qPCR (value in boldface type is statistically significant, P < 0.05); 4P-value of Log-rank Test.