Table 3.

Bilayer ASAQ tablet formulation for high dosage and low dosage ASAQ tablets

Composition	Content (%w/w)	Quantity (mg/tablet)
Layer 1 (blend no 30154C01 )		high dosage tablet (batch 30154C03)	low dosage tablet (batch 30154C04)
Dry granulated AQH	50.38	352.64	88.16
Sodium Croscarmellose (AcDiSol)	1.40	9.80	2.45
Polyvinylpyrrolidone (PVP K30)	1.14	8.00	2.00
Magnesium stearate	1.32	9.26	2.315
Silicon dioxide (Aerosil 300)	0.11	0.75	0.1875
Ca carbonate	7.71	54.00	13.50
Total layer 1	62.06	434.45	108.61
Layer 2 (blend 30154C03)
AS	14.29	100.00	25.00
Polyvinylpyrrolidone (PVP K30)	1.14	8.00	2.00
Sodium Croscarmellose (AcDiSol)	1.40	9.80	2.45
Magnesium stearate	0.43	3.00	0.75
Silicon dioxide (Aerosil 300)	0.11	0.75	0.1875
Calcium carbonate	7.71	54.00	13.50
Microcrystalline cellulose	12.86	90.00	22.50
Total layer 2	37.94	265.55	66.39
Total	100.00	700.00	175.00