Figure 6.

Positive selection acting on species clades. Positively selected sites identified on species clades are shown in a van der Waals representation on the SAL1 3D structure. Positively selected sites that matched amino acids involved in ligand binding are in yellow, the others in pink. Amino acids involved in ligand binding are in blue, the same as in Figure 4. Positively selected amino acids were identified by PAML computations using branch site models. A: in marmoset, B: in guinea pig, C: in horse, D: in mouse and E: in dog.