Table 1. Selected gene sets (pathways) significantly activated in all cell lines 24 h after non-lethal PDT.
Curated gene sets | Gene Ontology gene sets |
UV light response (24) | (Negative) regulation of cell cycle (4) |
Ionizing radiation response (3) | Cell cycle arrest (2) |
Hypoxia (5) | Apoptosis (4) |
Viral infection response (14) | Immune system process |
Interferon regulatory factor 4 targets (4) | Immune system development |
Interferon-beta pathway | Myeloid cell differentiation |
B lymphocyte development | B cell activation |
Upregulated in lymphoid stem cells | |
Proinflammatory genes | |
Neutrophil activation in wound healing |
The expression of 374 gene sets from a total number of 2483 curated gene sets and 129 from a total number of 996 Gene Ontology gene sets were found to be significantly upregulated by GSEA analysis (P<0.01). Numbers in parentheses indicate the number of different upregulated curated gene sets or Gene Ontology gene sets within this subset.