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. 2011 Jun 30;6(6):e21834. doi: 10.1371/journal.pone.0021834

Table 1. Selected gene sets (pathways) significantly activated in all cell lines 24 h after non-lethal PDT.

Curated gene sets Gene Ontology gene sets
UV light response (24) (Negative) regulation of cell cycle (4)
Ionizing radiation response (3) Cell cycle arrest (2)
Hypoxia (5) Apoptosis (4)
Viral infection response (14) Immune system process
Interferon regulatory factor 4 targets (4) Immune system development
Interferon-beta pathway Myeloid cell differentiation
B lymphocyte development B cell activation
Upregulated in lymphoid stem cells
Proinflammatory genes
Neutrophil activation in wound healing

The expression of 374 gene sets from a total number of 2483 curated gene sets and 129 from a total number of 996 Gene Ontology gene sets were found to be significantly upregulated by GSEA analysis (P<0.01). Numbers in parentheses indicate the number of different upregulated curated gene sets or Gene Ontology gene sets within this subset.