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. 2011 Jun 30;7(6):e1002153. doi: 10.1371/journal.pgen.1002153

Figure 2. Binding of RelA resembles the occupany pattern of Sirt6.

Figure 2

(A) Endogenous RelA targets the promoters of 2738 genes in the absence or presence of TNF-α. The heatmap displays the binding data as the degree of enrichment of ChIP DNA over total genomic DNA. (B) Shown are the gene ontologies (GO) terms significantly induced (pval<.05, Benjamini) among RelA targets in wild-type MEFs following treatment with TNF-α. Intensity of orange is representative of the degree of significance. (C) Shown are the motif modules significantly induced (pval<.05) among RelA targets in wild-type MEFs following treatment with TNF-α. Intensity of purple is representative of the degree of significance [-ln(pval)].