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. 2011 Jun 30;7(6):e1002138. doi: 10.1371/journal.pgen.1002138

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Each SNP was tested for an association with the indicated trait assuming an additive genetic model adjusted for age and sex. Meta-analysis was performed, and p-values (−log₁₀ transformed) of the meta-analysis are plotted along the y-axis using Synthesis-View [73], [74]. SNP location is given on the x-axis. Each triangle represents a meta-analysis p-value for each population. Populations are color-coded as follows: European Americans (blue; EA), African Americans (red; AA), Mexican Americans/Hispanics (orange; MA/H), and American Indians (purple; AI). Large triangles represent p-values at or smaller than genome-wide significance (p<10⁻⁸). The direction of the arrows corresponds to the direction of the beta coefficient. The significance threshold is indicated by the red bar at p = 0.05.