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. 2011 Jun;29(1):13–17. doi: 10.1159/000324123

Table 2.

Non-bile acid FXR and TGR5 modulators [25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37]

  • FXR

  • Bile alcohols

  • Polyunsaturated fatty acids

  • Xanthohumol

  • Drugs: fexaramine, GW4064, WAY-362450, thiazolidinediones

  • Oleanolic acid

  • 5-α-bile alcohols

  • Guggulsterone

  • Select RXR agonists

  • TGR5

  • Bile alcohols

  • Some neurosteroids

  • Oleanolic, betulinic and ursolic acids

  • Drugs: 2-aryl-3-aminomethylquinolines, 3-aryl-4-isoxazole-carboxamides