Table 2.
Central nervous system volume and lesion data (n=21)
| Variable | Mean ± SD (Range) |
|---|---|
| Normalized whole cord volume (x10−4)* | 9.28 ± 1.71 (7.46–13.55) |
| Normalized cervical cord volume (x10−4)* | 14.09 ± 0.22 (1.03–1.80) |
| Normalized thoracic cord volume (x10−4)* | 7.51 ± 0.15 (6.04–11.42) |
| Normalized C2–C3 cervical cord volume (x10−4)* | 1.49 ± (1.04–2.00) |
| Total cord T2 hyperintense lesion volume (mm3) | 214.9 ± 195.9 (0.0–624.2) |
| Cervical cord T2 hyperintense lesion volume (mm3) | 159.7 ± 179.1 (0.0–624.2) |
| Thoracic cord T2 hyperintense lesion volume (mm3) | 55.2 ± 99.5 (0.0–374.2) |
| BPF | 0.83 ± 0.05 (0.70–0.89) |
| Brain gray matter fraction | 0.49 ± 0.04 (0.41–0.55) |
| Brain white matter fraction | 0.34 ± 0.02 (0.293–0.40) |
| Brain FLLV (mm3) | 15221.0 ± 16586.8 (867.8–56749.6) |
Note: BPF=global brain parenchymal fraction; FLLV=fluid-attenuated inversion-recovery hyperintense lesion volume;
*
spinal cord volumes were normalized by number of slices and intracranial volume (see Methods section).