Table 1.

Summary of included trial eligibility and treatment regimens.

Trial	Included Disease Stage	Included Creatinine (μmol/L)	Induction Treatment	Maintenance Treatment
NORAM	Early Systemic	<150	MTX vs. oral CYC	MTX vs. oral CYC
CYCAZAREM	Generalized	150 – 499	oral CYC	Oral CYC vs. AZA
CYCLOPS	Generalized	150 – 499	IV CYC vs. oral CYC	AZA
MEPEX	Severe	≥ 500	PE+ oral CYC vs. IVMeP + oral CYC	AZA

MTX = methotrexate; CYC = cyclophosphamide; AZA = azathioprine; IV = intravenous; PE = plasma exchange; IVMeP = intravenous methylprednisolone