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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Hear Res. 2011 Jan 27;277(1-2):163–175. doi: 10.1016/j.heares.2011.01.012

Fig. 9.

Fig. 9

Modelled single-firing LSO cells decrease firing to changes in contralateral inhibition similarly in normal and dn/dn mice. A. AVCN/MNTB/LSO network showing ipsi and contralateral circuits. The ipsilateral ear is stimulated with constant amplitude (30% of maximum) and the contralateral ear (inhibitory) is stimulated with various amplitudes (see text). AVCN SBCs project excitatory terminals (open circles) to LSO dendrites. Contralateral AVCN GBCs project excitatory inputs to the ipsilateral MNTB that in turn send inhibitory terminals to the soma of ipsilateral LSO cells. Numbers on top represent the delay between each synapse (in ms). Examples of LSO single-unit response to fixed ipsilateral excitation of the AN (30% of the maximum stimulation amplitude) versus increasing contralateral inhibition (arriving from ipsilateral MNTB cells - 10% to 40% maximum stimulation amplitude of the contralateral AN) from the normal (B) and dn/dn (C) models. D. Summary of normalised firing frequency of SS units in normal (black line/squares) and dn/dn (grey line circles) network models. E. Summary of vector strength of MNTB neurons in relation to contralateral stimulus intensity in normal (black line/squares) and dn/dn (grey line circles).