Fig. 5.

Effect of anti-β1-integrin antibody, genistein, or cytochalasin D on internalizations of H. pylori into Huh 7 cells. Internalization was inhibited by anti-β1-integrin antibody (a), genistein (b), or cytochalasin D (c). Huh7 cells were co-cultured with H. pylori in the medium including above regents at the specified concentrations. Results are presented as the proportion of internalized bacteria versus control. The proportion of internalized bacteria was calculated as the rate of the number of internalized bacteria divided by the number of adherent bacteria. Data are presented as mean ± SEM of triplicate experiments.

*P < 0.05; ** P < 0.01