Table 1.
Demographic characteristics of patients and genotypes of hopQ, vacA and cagA
| Asian
|
Western
|
Total | P-value | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Korea | Japan | Thailand | Total | USA | Colombia | Total | ||||
| N | 127 | 120 | 38 | 285 | 173 | 99 | 272 | 557 | ||
| Sex | Male/female | 97/30 | 75/45 | 22/16 | 194/91 | 145/28 | 56/43 | 201/71 | 395/162 | <0.01 |
| Age | (mean ± SD) | 47.5 ± 1.2 | 56.9 ± 1.3 | 52.1 ± 1.5 | 52.1 ± 0.8 | 49.2 ± 1.1 | 55.9 ± 1.5 | 51.0 ± 0.9 | 54.5 ± 0.6 | <0.01 |
| Disease | Gastritis | 27.5% | 22.5% | 44.7% | 27.7% | 53.8% | 33.3% | 46.3% | 36.8% | <0.01 |
| GU | 21.3% | 27.5% | 15.8% | 23.2% | 17.3% | 0% | 11.0% | 17.2% | ||
| DU | 19.7% | 23.3% | 26.3% | 22.1% | 23.7% | 26.3% | 24.6% | 23.3% | ||
| GC | 31.5% | 26.7% | 13.2% | 27.0% | 5.2% | 40.4% | 18.0% | 22.6% | ||
| hopQ | Type I | 83.5% | 95.0% | 86.8% | 88.8% | 63.0% | 42.4% | 55.5% | 72.5% | <0.01 |
| Type II | 1.6% | 0% | 0% | 0.7% | 27.2% | 37.4% | 30.9% | 15.4% | ||
| Mix | 2.4% | 0% | 2.6% | 1.4% | 7.5% | 14.1% | 9.9% | 5.6% | ||
| Non-detection | 12.6% | 5.0% | 10.6% | 9.1% | 2.3% | 6.1% | 3.7% | 6.5% | ||
| vacA | s1m1 | 87.4% | 97.5% | 20.5% | 88.1% | 66.6% | 65.7% | 63.6% | 76.1% | <0.01 |
| s1m2 | 12.6% | 2.5% | 39.5% | 11.9% | 10.5% | 24.2% | 16.9% | 14.4% | ||
| s2m2 | 0% | 0% | 0% | 0% | 22.9% | 10.1% | 19.5% | 9.5% | ||
| cagA | Present | 97.6% | 100% | 100% | 98.9% | 85.0% | 79.8% | 83.1% | 91.2% | <0.01 |
| Absent | 2.4% | 0% | 0% | 1.1% | 15.0% | 20.2% | 16.9% | 8.8% | ||
DU, duodenal ulcer; GC, gastric cancer; GU, gastric ulcer; mix, mix type of hopQ type I and type II; SD, standard deviation.