Table 4.
Results of pooled sensitivity and specificity (95% CI) of the radiologist in assessing breast lesions on MRI with and without the use of a CAD system in general, stratified for experienced radiologists and residents with no or less experience (RANDOM effects model)
| Outcome or subgroup | Studiesa | Sensitivity (95% CI) | Specificity (95% CI) |
|---|---|---|---|
| Radiologist no CAD, general | 4b | 82% (72%–90%) | 81% (74%–87%) |
| Radiologist with CAD, general | 8c | 89% (83%–93%) | 81% (76%–85%) |
| Experienced radiologist no CAD | 4b | 89% (78%–94%) | 86% (79%–91%) |
| Experienced radiologist with CAD | 8c | 89% (81%–94%) | 82% (76%–87%) |
| Resident no CAD | 3d | 72% (62%–81%) | 79% (69%–86%) |
| Resident with CAD | 3d | 89% (80%–94%) | 78% (69%–84%) |
a In studies in which more than one radiologist/resident (blinded) assessed the images, the pooled calculation was based on all relevant radiologists in that study
b Meeuwis [27], Baltzer [24], Renz [28], Veltman [29]
c Arazi-Kleinmann [22] Meeuwis [27], Baltzer [23], Baltzer [24], Renz [28], Veltman [29], Hauth [25], Kelcz [26]