Effect of oral sucrose administration with or without xylitol on plasma glucose and insulin levels. After fasting for 18–20 h, the rats were orally administrated sucrose (1 g/kg body weight) either alone or with xylitol or mannitol (0.25 g/kg body weight). Blood samples were taken at 0, 30, 60 and 120 min after administration. (A, B) Time-dependent curve for plasma levels of (A) glucose and (B) insulin. Values are mean ± SEM, n = 4–7. *p<0.05 vs S group. S, sucrose (1 g/kg body weight); SX, sucrose (1 g/kg body weight) with xylitol (0.25 g/kg body weight); SM, sucrose (1 g/kg body weight) with mannitol (0.25 g/kg body weight).