Fig. 3.

Mitochondrial membrane potentials were investigated with JC-1. Fluorescence intensity was measured with plate reader DTX 880 at 18 h of 750 µM indomethacin treatments. The JC-1 fluorescence intensity of cells without indomethacin-treatment was significantly higher than that of indomethacin-treated cells. 24 h pretreatment of lansoprazole protected mitochondrial membrane potentials at almost normal levels (160.0 ± 29.0 vs 104.5 ± 26.3). *p<0.05 vs control.