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MIC of BTZ043 against three different mycobacterial species and their resistant mutants.
| Strain | MIC (ng/ml) |
Codon | Amino acid |
|---|---|---|---|
| M. smegmatis mc2155 | 4 | TGC | Cysteine |
| M. smegmatis MN47 | 4000 | GGC | Glycine |
| M. smegmatis MN84 | >16,000 | TCC | Serine |
| M. bovis BCG | 2 | TGC | Cysteine |
| M. bovis BCG BN2 | >16,000 | TCC | Serine |
| M. tuberculosis H37Rv | 1 | TGC | Cysteine |
| M. tuberculosis NTB9 | 250 | GGC | Glycine |
| M. tuberculosis NTB1 | 10,000 | TCC | Serine |
