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. 2011 Feb;178(2):525–536. doi: 10.1016/j.ajpath.2010.10.002

Figure 6.

Figure 6

Mechanistic exploration of PLA2G7 inhibition. A: Combinatorial effect of PLA2G7 silencing and oxidative stress on VCaP cell viability. Cell viability in samples not H2O2-treated but siRNA transfected was set as 100%. P values are compared with the scrambled control. B: Relative MT1X/MT2A and PLA2G7/ERG mRNA expression levels in primary prostate cancer samples. The relative mRNA expression for each gene in normal control sample was set as 1. C: Relative MT1X and MT2A mRNA expression levels after PLA2G7 silencing in VCaP cells. Relative mRNA expression level in the scrambled control was set as 100%. D: Relative PLA2G7 and ERG mRNA expression levels in VCaP cells after PLA2G7 and ERG silencing. Relative mRNA expression level in the scrambled control was set as 100%. *P < 0.05, **P < 0.01, ***P < 0.001.