| Typical antipsychotic agent |
| Haloperidol (Haldol®) |
0.25 mg to 0.5 mg per day |
0.25 mg to 4 mg per day |
Extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome |
| Atypical antipsychotic agents |
| Aripiprazole (Abilify®) |
5 mg per day |
2.5 mg to 15 mg per day |
Headache, agitation, anxiety, insomnia, somnolence, akathisia, light headedness, weight gain, nausea, dyspepsia, constipation, vomiting |
| Clozapine (Clozaril®) |
6.25 mg to 12.5 mg per day |
6.25 mg to 400 mg per day (slow titration) |
Agranulocytosis, neuroleptic malignant syndrome, deep venous thrombosis and pulmonary embolism, glucose dysregulation, weight gain, increased serum creatine kinase, increased serum lipids (including triglycerides), seizures, tachycardia, confusion, sedation, dizziness, salivary pooling |
| Olanzapine (Zyprexa®) |
2.5 mg per day |
2.5 mg to 15 mg per day |
Orthostatic hypotension, sedation, weight gain, glycemic dyscontrol, elevation of serum lipids (triglycerides), anticholinergic effects (e.g., constipation), nausea, dizziness (not orthostatic), tremor, insomnia, overactivation, akathisia, neuroleptic malignant syndrome, tardive dyskinesia |
| Quetiapine (Seroquel®) |
25 mg at bedtime |
50 mg to 400 mg at bedtime |
Sedation, orthostatic hypotension, dizziness, agitation, insomnia, headache, neuroleptic malignant syndrome |
| Risperidone (Risperdal®) |
0.25 mg to 0.5 mg at bedtime |
0.25 mg to 3 mg at bedtime |
Hypotension (especially orthostatic), tachycardia, dysrhythmias, electrocardiogram changes, syncope, sedation, headache, dizziness, restlessness, akathisia, anxiety, extrapyramidal symptoms, tardive dyskinesia, neuroleptic malignant syndrome |
| Ziprasidone (Geodon®) |
20 mg twice per day with food |
20 mg to 80 mg twice per day with food |
Extrapyramidal symptoms, somnolence, headache, dizziness, nausea, akathisia |
