Table 1.
Baseline Characteristics of Patients ≤65 years of Age with N1 Lymph Node Involvement
| Characteristic | Lymph Node Ratio | P-value | ||
|---|---|---|---|---|
| ≤0.15 (N=1,346) |
0.16-0.50 (N=1,737) |
≥0.5 (N=921) |
||
| Age, years, N (%) | ||||
| ≤50 | 255 (19) | 305 (18) | 160 (18) | 0.48 |
| 51-60 | 609 (45) | 838 (48) | 427 (46) | |
| ≥60 | 482 (36) | 594 (34) | 334 (36) | |
| Female, N (%) | 526 (39) | 707 (41) | 427 (46) | 0.002 |
| Race/Ethnicity, N (%) | ||||
| White | 1110 (83) | 1363 (79) | 661 (72) | <0.0001 |
| African American | 111 (8) | 200 (11) | 131 (14) | |
| Hispanic | 52 (4) | 60 (3) | 36 (4) | |
| Other | 73 (5) | 114 (7) | 93 (10) | |
| Married, N (%) | 908 (68) | 1112 (64) | 571 (62) | 0.02 |
| Histology, N (%) | ||||
| Adenocarcinoma | 646 (48) | 890 (51) | 546 (59) | <0.0001 |
| Squamous cell carcinoma | 498 (37) | 568 (33) | 214 (23) | |
| Large cell carcinoma | 71 (5) | 99 (6) | 60 (7) | |
| Bronchioalveolar cell carcinoma | 58 (4) | 89 (5) | 53 (6) | |
| Other | 73 (6) | 91 (5) | 48 (5) | |
| Tumor Location, N (%) | ||||
| Upper lobe | 772 (58) | 1001 (58) | 507 (55) | <0 .0001 |
| Middle lobe | 43 (3) | 76 (4) | 52 (6) | |
| Lower lobe | 404 (30) | 525 (30) | 315 (34) | |
| Other location | 127 (9) | 135 (8) | 47 (5) | |
| Tumor Status, N (%) | ||||
| T1A | 147 (11) | 187 (11) | 121 (13) | 0.01 |
| T1B | 207 (15) | 265 (15) | 174 (19) | |
| T2 | 154 (11) | 192 (11) | 112 (12) | |
| T2A | 415 (31) | 598 (35) | 284 (31) | |
| T2B | 173 (13) | 215 (12) | 103 (11) | |
| T3 | 250 (19) | 280 (16) | 127 (14) | |
| Type of Surgery, N (%) | ||||
| Lobectomy | 937 (70) | 1286 (74) | 770 (84) | <0.0001 |
| Pneumonectomy | 409 (30) | 451 (26) | 151 (16) | |
| Postoperative Radiation Therapy, N (%) | ||||
| Yes | 384 (28) | 670 (39) | 438 (48) | <0.0001 |
| No | 962 (72) | 1067 (61) | 483 (52) | |