Table 4.
Glycated proteins identified with the majority of their peptides having consistent up-regulation in AGT vs NGT blood plasma
| Gene Symbol | IPI No | Protein Name | Peptide Sequence | Peptide Count AGT | Peptide Count NGT |
|---|---|---|---|---|---|
| APOH | IPI:IPI00298828.3 | Beta-2-glycoprotein 1 | K.NGM* LHGDKVSFFCK#NK.E | 5 | 2 |
| APOH | IPI:IPI00298828.3 | Beta-2-glycoprotein 1 | K.NGMLHGDKVSFFCK#NK.E | 4 | NA |
| C4BPA | IPI:IPI00021727.1 | C4b-binding protein alpha chain | R.TPSCGDICNFPPK#IAHGHYK.Q | 9 | 5 |
| C4BPA | IPI:IPI00021727.1 | C4b-binding protein alpha chain | R.KPDVSHGEMVSGFGPIYNYK#DTIVFK.C | 8 | NA |
| C4BPA | IPI:IPI00021727.1 | C4b-binding protein alpha chain | R.KPDVSHGEM* VSGFGPIYNYK#DTIVFK.C | 3 | NA |
| C8B | IPI:IPI00294395.1 | Complement C8 beta chain | R.FRK#PYNVESYTPQTQGK.Y | 4 | 1 |
| C8B | IPI:IPI00294395.1 | Complement C8 beta chain | R.SDLEVAHYK#LKPR.S | 4 | 1 |
| CLU | IPI:IPI00291262.3 | Clusterin | R.KNPK#FM* ETVAEK.A | 6 | 3 |
| CLU | IPI:IPI00291262.3 | Clusterin | R.KNPK#FMETVAEK.A | 5 | 3 |
| F13A1 | IPI:IPI00297550.8 | Coagulation factor XIII A chain | K.KDGTHVVENVDATHIGK#LIVTK.Q | 7 | 1 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.EKGYPK#LLQDEFPGIPSPLDAAVECHR.G | 33 | 1 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.GGYTLVSGYPK#RLEK.E | 18 | 9 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.GDKVWVYPPEKK#EK.G | 11 | 4 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.GEFVWK#SHKWDR.E | 9 | 3 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.SLGPNSCSANGPGLYLIHGPNLYCYSDVEK#LNAAK.A | 8 | 3 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.GDK#VWVYPPEKK.E | 7 | 3 |
| HPX | IPI:IPI00022488.1 | Hemopexin | K.GEFVWK#SHK.W | 5 | NA |
| HRG | IPI:IPI00022371.1 | Histidine-rich glycoprotein | K.ALEK#YKEENDDFASFR.V | 7 | 2 |
| HRG | IPI:IPI00022371.1 | Histidine-rich glycoprotein | K.FK#SGFPQVSM* FFTHTFPK.- | 5 | 2 |
| IGL@ | IPI:IPI00154742.6 | IGL@ protein | K.ADSSPVK#AGVETTTPSK.Q | 6 | 2 |
| IGL@ | IPI:IPI00154742.6 | IGL@ protein | K.LTVLGQPK#AAPSVTLFPPSSEELQANK.A | 6 | 3 |
*
and # in peptide sequence represent oxidized methionine and Amadori compound modification, respectively. NA = not observed