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. Author manuscript; available in PMC: 2012 Jul 15.
Published in final edited form as: Bioorg Med Chem Lett. 2011 May 30;21(14):4238–4242. doi: 10.1016/j.bmcl.2011.05.078

Figure 4.

Figure 4

Sequence alignment of four segments of SHP2 interacting with C21. Residue numbers in SHP2 and PTP1B are labeled at the top and bottom, respectively. Residues within 5 Å of C21 in binding mode II are marked by *.