Table 1.
Self-reported fatigue in CMT patients
| Present study | (1) | ||||
|---|---|---|---|---|---|
| Study population | CMT1, CMT2, CMTX (with known genetic diagnosis) | Other/unclassified CMT | All CMT patients | CMT and concomitant disease | Elderly |
| n | 157 | 70 | 227 | 21 | 622 |
| Age (mean and SD) | 41.5 (11.0) | 42.2 (12.5) | 41.2 (12.6) | 50.4 (8.6) | 69.6 (6.8) |
| MFI-20 global score | 60.2 (5.1) | 59.5 (4.6) | 60.2 (4.9) | 60.6 (3.9) | 50.6 (16.9) |
| General fatigue | 11.1 (2.0) | 11.1 (1.7) | 11.2 (1.9) | 11.8 (2.2) | 10.6 (3.8) |
| Physical fatigue | 12.9 (1.8) | 12.6 (1.6) | 12.8 (1.8) | 12.3 (1.9) | 10.8 (4.3) |
| Mental fatigue | 11.4 (1.8) | 11.5 (1.7) | 11.4 (1.8) | 11.8 (1.9) | 9.0 (3.5) |
| Reduced activities | 12.7 (1.7) | 12.2 (1.7) | 12.6 (1.7) | 12.5 (2.0) | 10.5 (4.1) |
| Reduced motivation | 12.0 (2.3) | 12.1 (2.5) | 12.2 (2.3) | 12.3 (2.6) | 9.6 (3.4) |
Self-reported fatigue in CMT patients. Numbers depict mean and standard deviation (SD) of the MFI-20 global and domain scores. Patients with CMT and concomitant disease reached even higher scores. For comparison, the far right column (1) shows data obtained from 622 elderly people (>60 years) in the German general population [17]. Data obtained from patients who identified themselves as genetically diagnosed with CMT1, CMT2 or CMTX were combined since ANOVA analysis did not show any differences between these subgroups (Table 2)