Table 1.
Details of the 477-Patient Training Series Used for Gene Selection and Algorithm Training
| Characteristic | No. of patients | % of Series |
|---|---|---|
| Tumor size (cm) | ||
| <2 | 182 | 38 |
| 2–5 | 232 | 49 |
| >5 | 9 | 2 |
| NA | 4 | 11 |
| Age (years) | ||
| <50 | 97 | 20 |
| ≥50 | 331 | 69 |
| NA | 49 | 10 |
| ER status | ||
| Positive | 358 | 75 |
| Negative | 119 | 25 |
| Nodal involvement | ||
| Positive | 128 | 27 |
| Negative | 349 | 73 |
| Tumor grade | ||
| 1 (low) | 93 | 19 |
| 2 (moderate) | 234 | 49 |
| 3 (high) | 72 | 15 |
| NA | 78 | 16 |
| 10-year disease recurrence | ||
| No | 327 | 69 |
| Yes | 150 | 31 |
| Adjuvant therapy | ||
| None | 164 | 34 |
| Endocrine only | 205 | 43 |
| Systemic treatment | 108 | 23 |
The clinicopathological characteristics of the five independent validation series can be found in the referenced publications and in Supplemental Tables S1-S5 (available at http://jmd.amjpathol.org).
NA, not available.