Table 1.
Summary of Data in All Groupsa
| Factors | BMT | BMT + ATT | NLT | NLT + NTT | FLT | FLT + FTT |
|---|---|---|---|---|---|---|
| CD4 T cells | ↓ | → | → | ↑ | → | ↑ |
| CD8 T cells | ↓ | → | → | ↑ | ↑ | ↑↑ |
| % of FoxP3 in CD4 T cells | ↓ | ↓↓ | ↓ | ↓↓ | ↓ | ↓↓ |
| Gr-1/Mac-1 | ↓↓ | ↓↓↓ | ↓↓ | ↓↓↓ | ↓ | ↓↓ |
| % of EM CD4 T cells | → | ↑ | → | ↑↑ | → | ↑ |
| % of EM CD8 T cells | ↑ | ↑↑ | ↑ | ↑↑↑ | ↑ | ↑↑ |
| ConA | → | ↑ | → | ↑↑ | → | ↑↑ |
| IL-2 | → | ↑ | → | ↑ | → | ↑ |
| IFN-γ | → | ↑ | → | ↑↑ | → | ↑ |
a
Compared with nontreated controls. →, no change; ↑, mild increase, ↑↑, moderate increase; ↑↑↑, strong increase; ↓, mild decrease; ↓↓, moderate decrease; ↓↓↓, strong decrease.
ATT, adult thymus transplantation; BMT, bone marrow transplantation; ConA, concanavalin A; EM, effector memory; FLT, fetal liver cell transplantation; FTT, fetal thymus transplantation; IFN-γ, interferon γ; IL-2, interleukin 2; NLT, newborn liver cell transplantation; NTT, newborn thymus transplantation.