Table 1.
Symbol | ID | Expression ratio | |
---|---|---|---|
Rat neural stem cell genes | |||
Differentiation | |||
Glial fibrillary acidic protein | Gfap | 24387 | 44.8a |
Bone morphogenetic protein 4 | Bmp4 | 25296 | 2.7 |
Meteorin | Metrn | 287151 | 2.2 |
Notch signaling | |||
Delta-like 1 | Dll1 | 84010 | 2.5b |
Intracellular signaling/transcription factors | |||
Lymphoid enhancer binding factor 1 | Lef1 | 161452 | 4.1 |
Tribbles homolog 1 | Trib1 | 78969 | 4.0b |
Protein tyrosine phosphatase N | Ptprn | 116660 | 3.4 |
Protein tyrosine phosphatase 5 | Ptpn5 | 29644 | 2.7b |
Protein kinase C eta | Prkch | 81749 | 2.5 |
Early growth response 1 | Egr1 | 24330 | 2.3 |
Signan transducer and activator of transcription 3 | Stat3 | 25125 | 2.1 |
Myelin related proteins | |||
Discoidin domain receptor family 1 | Ddr1 | 25678 | 2.3 |
Plasma membrane proteolipid | Pllp | 64364 | 2.2 |
Gelsolin | Gsn | 296654 | 2.2 |
Regulators in development | |||
Reelin | Reln | 24718 | 7.5 |
Netrin 1 | Ntn1 | 114523 | 2.6 |
Chondroitin sulfate proteoglycan 2 | Cspg2 | 114122 | 2.1 |
Human mesenchymal stromal cell genes | |||
Notch signaling | |||
Hairy and enhancer of split 1 | HES1 | 3280 | 5.4 |
Notch homolog 3 | NOTCH3 | 4854 | 5.0 |
Jagged 1 | JAG1 | 182 | 4.2 |
SMAD family member 3 | SMAD3 | 4088 | 2.7 |
Secreted factors | |||
Bone morphogenetic protein 1 | BMP1 | 649 | 3.3 |
Hepatocyte growth factor | HGF | 3082 | 3.2 |
Transforming growth factor beta 3 | TGFB3 | 7043 | 3 |
Transforming growth factor beta 1 | TGFB1 | 7040 | 2.4 |
Cell surface receptors | |||
Thy-1 cell surface antigen | THY1 | 7070 | 2.3 |
KIT ligand | KITLG | 4254 | 2.3 |
Glypican 1 | GPC1 | 2817 | 2.3 |
Using a 90% confidence interval, change in transcript expression was not found to be significant due to high variance between individual perfect match and mismatch probes. Signal absent in NSCs alone.
Signal absent in NSCs alone.
NSC, neural stem cell.