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. 2011 May 31;5:89. doi: 10.1186/1752-0509-5-89

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Copyright ©2011 Chu et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Partial correlations and Pearson correlations. Panel (a-b) show the distribution of Fisher-transformed partial correlation (a) and Pearson correlation coefficients (b) from the simulated "case" and "control" data sets. The red dots represents the differentially connected edges. Panel (c-f) show the histograms of z-statistics , where z_ijcand z_ijdare the Fisher-transformed correlation coefficients from the "case" and "control" data sets, respectively. Panel (c-d) are for all edges and panel (e-f) are for the truly differentially connected edges only.

Inline graphic — Partial correlations and Pearson correlations. Panel (a-b) show the distribution of Fisher-transformed partial correlation (a) and Pearson correlation coefficients (b) from the simulated "case" and "control" data sets. The red dots represents the differentially connected edges. Panel (c-f) show the histograms of z-statistics , where z_ijcand z_ijdare the Fisher-transformed correlation coefficients from the "case" and "control" data sets, respectively. Panel (c-d) are for all edges and panel (e-f) are for the truly differentially connected edges only.