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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Vet Anaesth Analg. 2011 May;38(3):231–239. doi: 10.1111/j.1467-2995.2011.00605.x

Table 1.

Summary of isoflurane MAC measurements (%, mean ± SD) in rats receiving intrathecal aCSF (control) versus rats receiving intrathecal picrotoxin in aCSF. There was no difference between the first and second MAC measurements for any treatment in either group. Post-MK801 MAC was significantly decreased from baseline in both groups. Isoflurane MAC was significantly higher in the picrotoxin animals than the control animals. The ΔMAC was significantly lower in the picrotoxin animals than the control animals

Measurement Control (n = 5) Picrotoxin (n = 9)
Baseline
 MAC 1 1.56 ± 0.08 1.80 ± 0.21
 MAC 2 1.53 ± 0.02 1.76 ± 0.23
Post-MK801
 MAC 1 0.78 ± 0.11 1.32 ± 0.26
 MAC 2 0.86 ± 0.08 1.30 ± 0.21
ΔMAC 0.72 ± 0.07 0.47 ± 0.14