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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Immunol. 2011 May 25;187(1):325–336. doi: 10.4049/jimmunol.1003523

Figure 4. Development of a B6 mouse having a targeted mutation in the CD101 gene.

Figure 4

A, The strategy used to generate a CD101 null mouse is depicted. Details are included in the Materials and Methods section. B–E, CD101 expression on various cell subsets and lack of expression on cells from B6 CD101 null mice. B, Bone marrow and spleen cells were gated by light scatter (see Supplemental Fig. 3 for examples of light scatter gating) to include all cells except erythrocytes and analyzed for CD101 and Gr1 expression. C, Splenic CD4+ T cells were assessed for CD101, CD44 and FoxP3 expression. See text for further details. Data shown are representative of at least 3 independent experiments.