Figure 1.

Trachomatous trichiasis cases do not differ in proliferative responses to Chlamydia trachomatis antigens compared to controls. PBMCs log₁₀ stimulation index (test antigen c.p.m/non-stimulated c.p.m) were calculated after 6 days of stimulation with PWM or chlamydial antigens EBs, MOMP, Enolase, PmpD, PmpG, Omp2. Trichiasis cases (•) and disease free endemic controls (○). Paired students t-test was performed on each group (up to 42 pairs). The dashed line represents stimulation index = 2. All responses above this dashed line were considered above background. Each antigen induced a statistically significant response above background. No statistical significance was detected between proliferative responses of the clinical groups to any chlamydial antigen. Analysis based on the proportion of responder (SI > 2) versus non-responder (SI < 2) also found that there were no differences evident between the clinical groups.